Lisinopril is used to treat elevated blood pressure and heart failure.
How to use
Lisinopril should be taken at doses specifically directed by the physician. Lisinopril can be taken with or without food. Lisinopril should be taken at the same time each day to maintain consistent blood levels. Lisinopril should not be taken within two hours of taking an antacid since the antacid binds lisinopril and prevents its absorption. Lisinopril is often tapered when discontinuing.
Drug Class and Mechanism
Lisinopril is an angiotensin converting enzyme (ACE) inhibitor. Angiotensin is a chemical that is made by the body continuously. It narrows blood vessels and thereby maintains (elevates) blood pressure. When the enzyme is blocked by lisinopril, angiotensin cannot be converted into its active form. As a result, blood pressure falls.
Interestingly, lisinopril and other ACE inhibitors were developed from the venom of a poisonous Brazilian snake.
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.
Lisinopril should be stored in a dry place at 15-30 degrees C (59-86 degrees F).
Possible Side Effects
First doses of lisinopril can cause dizziness due to a drop in blood pressure. Lisinopril should be stopped if there are symptoms or signs of an allergic reaction including feelings of swelling of the face, lips, tongue or throat. Severe allergic reactions (anaphylaxis) and hives occasionally occur.
An uncommon but dangerous side effect is a drop in the white blood cells which fight infection. Cough is a known side effect of this drug.
Lisinopril can impair the function of the kidneys, and every person taking this medication should have their kidney function checked. Lisinopril rarely can cause nausea, headaches, anxiety, insomnia, drowsiness, nasal congestion and sexual dysfunction.
If you experience any of the following serious side effects, stop taking lisinopril and call your doctor immediately or seek emergency medical treatment:
an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
little or no urine;
an irregular heartbeat or changes in your heartbeat;
severe dizziness or fainting; or
signs of an infection including a sore throat or a fever.
Other, less serious side effects may be more likely to occur. Continue to take lisinopril and talk to your doctor if you experience
mild dizziness or lightheadedness;
unusual fatigue or weakness;
dry, tickling cough;
numbness or tingling in the hands, feet, arms, or legs;
nausea, vomiting, or diarrhea;
a rash; or
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
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